So I am hoping there is some way I can force iTunes to save the current state of tag info to the files!Ībout the 2 drives, it's simple. Regardless of how it is supposed to work or what the explanation is, the situation now stands that my tags display perfectly in iTunes but are not all saved to the files perfectly. I don't understand it either, but from research I have done online, it may have something to do with an iTunes glitch relating to the ID3 tag version. But yes, strangely enough, even though the tags show up properly in iTunes, they do not show up properly in other players, and don't show up properly in iTunes if I remove the album, copy the album to the second drive, and load it back into iTunes (only for a portion of the files, but with the size of my collection this would still be time consuming to fix). I also thought it could have something to do with read only, so I made sure that the files were not read only. Yes, they are mp3 files, and yes, I had assumed what you told me, that changes made in iTunes would be made to the mp3 files. Lastly, if neither of the above are possible, is there an easy way to backup the iTunes database so that all my tags and artwork are present once I remove the current drive and re-load my collection into iTunes from the new drive? Will the change of path prevent me from being able to backup the database? I've also been disappointed to find out that when adding album artwork, iTunes does not actually save the artwork to the ID3 tags as I assumed. So my question is this: is there some way to force iTunes to save the data that is currently displayed in iTunes to the ID3 tags? It seems iTunes is perhaps storing this tag info in some kind of internal database? To be specific I am not talking about meta-data like ratings and number of times played. If I load them into another application or reload them into iTunes from the new drive, not all the tag changes I made in iTunes are showing up. However, in the process I've noticed that not all the changes that I made to the tags have actually saved to the tags themselves, even though they continue to display correctly in iTunes. Now I want to back up the entire drive (F: drive, I keep my music on a separate drive) to a new hard drive (H: drive).
I just spent a very (very) long time going through my entire music collection making sure all album art is present and all tags are corrected to my preferences. Overall integrative analysis identified an interrelated gene network affected by copy number and mutation, leading to disruption of the p53 pathway and the BCR→PI3K or NF-κB activation, which can be further exploited in vivo by small-molecule inhibitors for effective therapy in adult-mBL.Desperately need some help. In vitro studies suggested miR-17∼92's role in constitutive activation of BCR signaling and sensitivity to ibrutinib. Gain/amplification of MIR17HG and its paralogue loci was observed in 50% of adult-mBL. These double-hit lymphomas may have arisen from a tumor precursor that acquired both BCL2 and MYC translocations and/or KMT2D ( MLL2) mutation. A subset of adult-mBL had BCL2 translocation and mutation and elevated BCL2 mRNA and protein expression, but had a mutation profile similar to mBL. Mutations in genes promoting the tonic B-cell receptor (BCR)→PI3K pathway ( TCF3 and ID3) did not differ by age, whereas effectors of chronic BCR→NF-κB signaling were associated with adult-mBL. Adult-mBL had either unique or more frequent genomic aberrations (del13q14, del17p, gain8q24, and gain18q21) compared with pediatric-mBL, but shared commonly mutated genes.
High-resolution structural and functional genomic analysis of adult Burkitt lymphoma (BL) and high-grade B-cell lymphoma with BL gene signature (adult-molecularly defined BL ) revealed the MYC-ARF-p53 axis as the primary deregulated pathway.
The adult high-grade B-cell lymphomas sharing molecular features with Burkitt lymphoma (BL) are highly aggressive lymphomas with poor clinical outcome.
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